The Most Important Articles in Heart Failure
Below are what I believe to be the most important articles in heart failure in mid-2015. Most of the ICD trials are actually covered in the EP trials section. Each trial is divided into categories, and each blue trial name is a link to the trial page. In many cases where the journal article is open access, the link will open the full article. Otherwise, a Pubmed or Abstract page will open. Enjoy!
Beta Blockers
CAPRICORN (carvedilol)
CIBIS-I, CIBIS-II (bisoprolol)
MERIT-HF (metoprolol XL)
BEST (bucindolol)
COPERNICUS (carvedilol)
COMET (carvedilol vs. metoprolol)
MOCHA (carvedilol)
SENIORS (nevibolol)
OPTIMIZE-HF (beta blockers)
ACE Inhibitors
HOPE (ramipril)
SOLVD (enalapril)
SAVE (captopril)
ATLAS (lisinopril dosing)
CONSENSUS (enalapril)
OPTIMAAL (losartan vs. captopril)
VALIANT (valsartan, captopril)
Angiotensin Receptor Blockers
CHARM, CHARM-ALTERNATIVE, CHARM-PEF (candesartan)
I-PRESERVE (irbesartan, HFpEF)
PEP-CHF (perindopril)
TOPCAT (spironolactone, HFpEF)
Aldo-DHF (spironolactone, HFpEF)
Other Therapies
SCD-HeFT (amiodarone vs. ICD)
ALLHAT (thiazide diuretics & HTN)
DIG (digoxin)
RALES (spironolactone)
EPHESUS (eplerenone)
EMPHASIS-HF (eplerenone)
TREAT (darbapoietin-alpha)
RED-HF (darbapoietin-alpha)
DOSE (furosemide, bolus vs. continuous)
ASCEND-HF (nesiritide)
REMATCH (LVAD)
Guidelines
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