The Most Important Articles in Ischemic Heart Disease, Coronary Artery Disease, and Myocardial Infarction (MI)
Below are what I believe to be the most important articles in coronary heart disease in mid-2015. Each trial is divided into categories, and each blue trial name is a link to the trial page. In many cases where the journal article is open access, the link will open the full article. Otherwise, a Pubmed or Abstract page will open. Enjoy!
Coronary Artery Bypass Grafting (CABG)
PCI
SIRIUS (sirolimus DES)
TAXUS-IV (paclitaxel DES)
STREAM (rescue PCI)
TRANSFER-AMI (rescue PCI)
DEFER (FFR)
FAME (FFR)
CABG vs. PCI
Medical/Adjunctive Therapy for Ischemia/Infarct
HOPE (ramipril)
OASIS-V (enoxaparin vs. fondaparinux)
SYNERGY (enoxaparin vs. unfractionated heparin)
TIMI-11b (enoxaparin vs. unfractionated heparin in UA/NSTEMI)
Antiplatelet Trialists’ Intervention: High Risk Low Risk
CURRENT/OASIS-7 (aspirin & clopidogrel factorial)
CURE (clopidogrel)
TRITON/TIMI-38 (prasugrel vs. clopidogrel)
TRILOGY-ACS (prasugrel vs. clopidogrel)
PLATO (ticagrelor vs. clopidogrel)
COGENT (clopidogrel/PPI)
GRAVITAS (clopidogrel dosing)
ACUITY (heparin+GPIIb/IIIa vs. bivalirudin+GPIIb/IIIa vs. bivalirudin)
HORIZONS-AMI (bivalirudin)
CAPTURE (abciximab)
EARLY-ACS (eptifibatide)
COMMIT (beta blocker, acute MI)
POISE (toprol XL)
DECREASE (bisoprolol, perioperative)
TRIUMPH (tilarginine, shock)
WOEST (clopidogrel without aspirin)
CREDO (clopidogrel)
GUSTO-1 GUSTO-3 (t-PA, streptokinase)
GISSI-1 GISSI-2 (streptokinase, alteplase)
ISIS-2 (streptokinase)
INTIME-2 (lanoteplase)
ASSENT-2 (tenecteplase vs. alteplase)
Cholesterol-Lowering Drugs and Outcome
PROVE-IT/TIMI-22 (pravastatin/atorvastatin)
A-TO-Z (simvastatin)
Acute Pericarditis
ICAP (colchicine)
COPE (colchicine)
Scoring Systems in AMI
Guidelines
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